You feel that angular cheilitis is winning the war and you need reinforcements to turn the tide. Consequently, you see your dermatologist who recommends a dose of the synthetic antifungal agent, fluconazole (diflucan). Will this pill unequivocally knock out the cheilitis so that you can resume a normal, peaceful existence?

Remember, most cases of perleche arise from bellicose bacteria or fungi. Now, if your angular cheiliis is driven by bacteria, diflucan may very well prove ineffective. However, if the condition is caused by Candida albicans and/or other fungal infections, diflucan may contribute to its demise.

What is Fluconazole / Diflucan?

Used to arrest the development of fungal infections, diflucan is an oral anti-fungal medication. It will not treat viral infections, such as the cold or flu, or those that are created by wayward bacteria. This is why it is not a recommended course of treatment for bacterial-created angular cheilitis.

Physicians typically prescribe 400 mg of diflucan as a first dose, followed by a two-times a day protocol of 100 mg. Symptoms may subside after a few days but it is recommended to complete the two-week dose, ensuring the complete decimation of the fungi. If you forgot one dose, you’re supposed to skip it and not take two pills at once to make up for the forgotten pill.

What are Diflucan’s Side Effects?

Although diflucan is typically well-tolerated in most individuals, there are a slew of potential side effects, including: abdominal pain, bowel issues, accelerated heartbeat, skin problems, such as the development of hives, dizziness, fever, chest pain, sore throat, and a host of other maladies. Remember, this is a drug, and unfortunately, while it may be helpful to thwart the cheilitis, it can foster unwanted side effects. Of course, consult with your physician should you experience any type of discomfort while on the medication.

Also, the doctor will ensure that you’re a suitable candidate for this medication. Folks with kidney or liver disease, for example, should not be given this drug – but again, this is within the realm of your doctor’s decision. The safety of diflucan has not been established for women who are pregnant or breastfeeding.

Should You Take Diflucan for Your Angular Cheilitis?

This is a personal decision and we offer a biased viewpoint. We are holistic by nature and any oral medication to us should be a last resort and not a first resort. The drug is very costly (perhaps your insurance company will cover it), may stir up adverse side effects, and may not even eradicate your angular cheilitis if fungi are not the offending culprits.

We prefer more natural interventions, but for those who have tried the proverbial kitchen sink and want to go for the ‘stronger stuff, diflucan may be your drug of choice to defeat angular cheilitis.

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